CAS 5337-93-9 4-Methylpropiophenone

CAS 5337-93-9 4-Methylpropiophenone

CAS 5337-93-9 4-Methylpropiophenone

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CAS 5337-93-9 4-Methylpropiophenone Product Details

What’s the Usage of CAS 5337-93-9 4-Methylpropiophenone?

4′-methylpropiophenone has been reported to be used in the synthesis of pharmaceutical compounds such as tolperisone and other muscle relaxants. The substance is also a starting material in the synthesis of 4-methylmethcathinone (mephedrone). Mephedrone has been encountered as a ‘legal high’ and on the illicit drug market masquerading as cocaine (in powder form), MDMA (in tablet form) and as an adulterant. According to the 2016 European Drugs Market Report produced by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), mephedrone has created a specific demand and carved its own distinct market share.

Synthesis of CAS 5337-93-9 4-Methylpropiophenone:

4′-Methylpropiophenone can be synthesized through various methods. One common approach involves the reaction of propiophenone with methylmagnesium bromide or methyl lithium in the presence of a catalyst. Another method utilizes Friedel-Crafts acylation, where propiophenone is acylated with methyl chloride or methyl bromide using a Lewis acid catalyst. These methods allow for the controlled introduction of the methyl group onto the phenyl ring.

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